Has my patient an acute myocardial infarction?
If a patient just had a cardiac attack, this person can tell a medical professional about the symptoms. Some symptoms like tightness in the chest with acute pain in the left shoulder and arm are typical signals for a heart attack. However there are other symptoms like pain in the stomach or in the belly that could be caused by a cardiac infarction. Otherwise such symptoms can originate from other diseases. It’s always a challenge for every physician or medical professional to find the correct diagnose.
With BelCARDIO you can determine immediately whether a hospitalization is necessary or if other reasons are the cause for thorax pain. A quick decision can help the patient and it’s a relief for your daily work.
hFABP (heart-specific human fatty-acid binding protein) is actively involved in the lipid acid metabolism with a clinical cut-off of 7.0 ng/mL. Measurable release starts already 20 min after the event and elevated concentrations can be found in plasma for about 24 h before returning to normal.
Cardiac Troponin I (cTnI) is present in the heart muscle and forms a complex with Troponin T and Troponin C. The complex will disrupt in case of myocardial damage and the components are released into circulation, where they can be detected in about 4 hours after the start of the event. Elevated levels of Troponin I remain detectable for 8 days after release, providing a large time window for diagnostic confirmation of an ischemic heart lesion. The clinical cut-off is 0.5 ng/mL.
The function of hFABP and Troponin in the body
The graph shows the appearance and disappearance of both biomarkers (hFABP and Troponin I) in the timely context after a myocardial event. Troponin I is considered to be the “gold standard” of infarction diagnostics because of a high specificity and sensitivity. hFABP increases very quickly after the event and is therefore an optimal marker to exclude an acute myocardial infarction also with very high specificity and sensitivity.